Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | AOC2 | O75106 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19305271 | 0.85 | ALOX15 (0.60) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL2020142 | 0.84 | GPR174 (0.60) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL13221027 | 0.81 | ALOX15 (0.56) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL12535812 | 0.81 | ALOX15 (0.56) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL10370966 | 0.81 | ALOX15 (0.56) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL7746 | 0.81 | ALOX15 (0.68) | ALOX15LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1486040 | 0.81 | GPR174 (0.62) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL9538610 | 0.81 | ALOX15 (0.56) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL194404 | 0.79 | ALOX15 (0.65) | ALOX15ALDH1A1RECQLLMNAKCNA3 | |
| SCHEMBL2778615 | 0.78 | CA12 (0.52) | ALDH1A1LMNACYP2C9SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |
| EP-0586418-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AG (DE) | 1994-03-16 | — | — | EP | claimed |
| US-5276008-A | Herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| WO-1992020663-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | claimed |
| EP-0502307-A2 | Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones | BAYER AG (DE) | 1992-09-09 | — | — | EP | claimed |
| EP-0033088-B1 | ANTIMYCOTIC AGENTS | BAYER AG (DE) | 1983-05-25 | — | — | EP | claimed |
| EP-0033088-A2 | Antimycotic agents | BAYER AG (DE) | 1981-08-05 | — | — | EP | claimed |
| US-20220135557-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-05-05 | — | — | US | disclosed |
| US-20220119382-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-04-21 | — | — | US | disclosed |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-15 | — | — | US | disclosed |
| CN-113683610-A | RET inhibitor, pharmaceutical composition and application thereof | 广东东阳光药业有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-113683611-A | RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-113620945-A | RET inhibitor, pharmaceutical composition thereof and application thereof in medicines | 广东东阳光药业有限公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-0007505-A2 | Alpha-azolyl-beta-hydroxy-ketones, process for their preparation and their use as fungicides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |
| EP-0007506-A1 | Derivatives of alpha-azolyl ketones, processes for their preparation and their use as fungicides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |
| US-4147869-A | ADRENERGIC BLOCKING AGENTS FOR TREATMENT OF ANGINA PECTORIS, ARRHYTHMIA AND HYPERTENSION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4119729-A | TREATMENT OF HYPERTENSION | MEAD JOHNSON & COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4067904-A | ANTIARRHYTHMIA, HYPOTENSIVE | MEAD JOHNSON & COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-3954984-A | ANTISECRETRETORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954981-A | Triazolocycloalkylhydrothiadiazine derivatives | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119382-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | RET, SLC10A2, REL | ALOX15 1096/4885ALDH1A1 2416/4885RECQL 1318/4885 |
| US-20220135557-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | RET, REL, SLC10A2 | ALOX15 1267/4885ALDH1A1 2845/4885RECQL 1611/4885 |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | CRH, MC2R, HTR3C | ALOX15 1816/4885ALDH1A1 1739/4885RECQL 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.