SCHEMBL1065641

SCHEMBL1065641

CCOC(=O)CNC(=O)OCCOCCNC(=O)OCCOCCNC(=O)OCCOCCNC(=O)OCCOC(C)N

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.36
CHRNB2 P17787 2/20 0.35
CHRNB4 P30926 2/20 0.35
CHRNA3 P32297 2/20 0.35
CHRNA4 P43681 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PPIB P23284 1/20 0.33
PPIA P62937 1/20 0.33
PPID Q08752 1/20 0.33
PPIG Q13427 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1064713 1.00 ACHE (0.39) ACHEMEN1KMT2AGAACHRNB2
SCHEMBL1064714 0.84 ACHE (0.42) ACHEMEN1KMT2AGAAL3MBTL1
SCHEMBL1065642 0.84 ACHE (0.42) ACHEMEN1KMT2AGAAL3MBTL1
SCHEMBL3364343 0.83 TLR2 (0.35) ACHEMEN1KMT2AGAACHRNB2
SCHEMBL1064998 0.80 ACHE (0.41) ACHEMEN1KMT2AGAAL3MBTL1
SCHEMBL1061879 0.80 ACHE (0.41) ACHEMEN1KMT2AGAAL3MBTL1
SCHEMBL3361834 0.80 ACHE (0.41) ACHEMEN1KMT2AGAAL3MBTL1
SCHEMBL20469924 0.76 ACHE (0.46) ACHEMEN1KMT2ACHRNB2CHRNB4
SCHEMBL18685483 0.73 TDP1 (0.39) GAALMNA
SCHEMBL11141024 0.72 ACHE (0.52) ACHEMEN1KMT2AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450469-B2 Synthesis of peptide nucleic acids conjugated with amino acids and their application PANAGENE INC. (KR) 2013-05-28 US disclosed
US-20110014715-A1 Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application PANAGENE INC. (KR) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014715-A1 Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application CPSF6, RNGTT, DNPEP ACHE 4498/4885MEN1 4198/4885KMT2A 1168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.