SCHEMBL1065642

SCHEMBL1065642

CCOC(=O)CNC(=O)OCCOCCNC(=O)OCCOCCNC(=O)OCCOCCNC(=O)OCCOCCN

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.42
GAA P10253 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.37
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TLR2 O60603 1/20 0.36
PPIB P23284 1/20 0.35
PPIA P62937 1/20 0.35
PPID Q08752 1/20 0.35
PPIG Q13427 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1064714 1.00 ACHE (0.42) ACHEGAAL3MBTL1CYP1A2LMNA
SCHEMBL3364343 0.88 TLR2 (0.35) ACHEGAAL3MBTL1TLR2ALDH1A1
SCHEMBL9980552 0.86 L3MBTL1 (0.43) ACHEL3MBTL1LMNASMN1; SMN2TLR2
SCHEMBL3361834 0.84 ACHE (0.41) ACHEGAAL3MBTL1CYP1A2ALDH1A1
SCHEMBL1064998 0.84 ACHE (0.41) ACHEGAAL3MBTL1CYP1A2ALDH1A1
SCHEMBL1061879 0.84 ACHE (0.41) ACHEGAAL3MBTL1CYP1A2ALDH1A1
SCHEMBL1064713 0.84 ACHE (0.39) ACHEGAAL3MBTL1LMNASMN1; SMN2
SCHEMBL1065641 0.84 ACHE (0.39) ACHEGAAL3MBTL1LMNASMN1; SMN2
SCHEMBL3364338 0.81 ACHE (0.36) ACHEL3MBTL1CYP1A2LMNASMN1; SMN2
SCHEMBL4761785 0.80 ACHE (0.44) ACHELMNASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450469-B2 Synthesis of peptide nucleic acids conjugated with amino acids and their application PANAGENE INC. (KR) 2013-05-28 US disclosed
US-20110014715-A1 Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application PANAGENE INC. (KR) 2011-01-20 US disclosed
WO-2009093821-A9 SYNTHESIS OF PEPTIDE NUCLEIC ACIDS CONJUGATED WITH AMINO ACIDS AND THEIR APPLICATION 주식회사 파나진 (KR) 2010-05-27 WO disclosed
WO-2009093821-A2 SYNTHESIS OF PEPTIDE NUCLEIC ACIDS CONJUGATED WITH AMINO ACIDS AND THEIR APPLICATION PANAGENE INC. (KR) 2009-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014715-A1 Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application CPSF6, RNGTT, DNPEP ACHE 4498/4885GAA 515/4885L3MBTL1 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.