SCHEMBL10656533

SCHEMBL10656533

O=C(c1ccc(Cl)c(C(F)(F)F)c1)c1ccc(Cl)c(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.56
NPFFR2 Q9Y5X5 1/20 0.53
CHEK2 O96017 1/20 0.52
PDK1 Q15118 1/20 0.50
SRD5A2 P31213 1/20 0.48
HSD11B1 P28845 1/20 0.48
HTR3E A5X5Y0 1/20 0.47
HTR3B O95264 1/20 0.47
HTR3A P46098 1/20 0.47
HTR3D Q70Z44 1/20 0.47
HTR3C Q8WXA8 1/20 0.47
VCAM1 P19320 1/20 0.46
SLC6A3 Q01959 1/20 0.45
PGR P06401 1/20 0.45
GRM4 Q14833 1/20 0.44
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
IDO1 P14902 1/20 0.43
TRPV1 Q8NER1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23388266 0.91 VCAM1 (0.53) KDRNPFFR2CHEK2PDK1SRD5A2
SCHEMBL8175719 0.91 KDR (0.49) KDRNPFFR2CHEK2PDK1SRD5A2
SCHEMBL23270210 0.90 CHEK2 (0.52) KDRNPFFR2CHEK2PDK1SRD5A2
SCHEMBL1794695 0.86 KDR (0.54) KDRNPFFR2CHEK2PDK1HSD11B1
SCHEMBL31542016 0.86 KDR (0.54) KDRNPFFR2CHEK2PDK1HSD11B1
SCHEMBL375961 0.86 TSHR (0.59) KDRNPFFR2PDK1SRD5A2HSD11B1
SCHEMBL23388234 0.86 TRPV1 (0.47) KDRNPFFR2CHEK2TRPV1
SCHEMBL8177157 0.86 MAPT (0.53) KDRNPFFR2CHEK2LMNAGAA
SCHEMBL1086197 0.85 NPFFR2 (0.58) KDRNPFFR2CHEK2PDK1HSD11B1
Hydrochloric Acid SCHEMBL6369011 0.85 TSHR (0.57) KDRNPFFR2PDK1SRD5A2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9653745-B2 Block copolymer, manufacturing method therefor, and polymer electrolyte material, molded polymer electrolyte, and solid-polymer fuel cell using said block copolymer TORAY INDUSTRIES, INC. (JP) 2017-05-16 US disclosed
US-9653745-B2 Block copolymer, manufacturing method therefor, and polymer electrolyte material, molded polymer electrolyte, and solid-polymer fuel cell using said block copolymer TORAY INDUSTRIES, INC. (JP) 2017-05-16 US disclosed
EP-2749585-B1 BLOCK COPOLYMER, MANUFACTURING METHOD THEREFOR, AND POLYMER ELECTROLYTE MATERIAL, MOLDED POLYMER ELECTROLYTE, AND SOLID-POLYMER FUEL CELL USING SAID BLOCK COPOLYMER TORAY INDUSTRIES (JP) 2017-03-22 EP disclosed
US-20140193742-A1 BLOCK COPOLYMER, MANUFACTURING METHOD THEREFOR, AND POLYMER ELECTROLYTE MATERIAL, MOLDED POLYMER ELECTROLYTE, AND SOLID-POLYMER FUEL CELL USING SAID BLOCK COPOLYMER TORAY INDUSTRIES, INC. (JP) 2014-07-10 US disclosed
US-20140193742-A1 BLOCK COPOLYMER, MANUFACTURING METHOD THEREFOR, AND POLYMER ELECTROLYTE MATERIAL, MOLDED POLYMER ELECTROLYTE, AND SOLID-POLYMER FUEL CELL USING SAID BLOCK COPOLYMER TORAY INDUSTRIES, INC. (JP) 2014-07-10 US disclosed
EP-2749585-A1 BLOCK COPOLYMER, MANUFACTURING METHOD THEREFOR, AND POLYMER ELECTROLYTE MATERIAL, MOLDED POLYMER ELECTROLYTE, AND SOLID-POLYMER FUEL CELL USING SAID BLOCK COPOLYMER Toray Industries, Inc. (JP) 2014-07-02 EP disclosed
CN-1262679-A IL-5 inhibiting 6-azauracil derivatives JANSSEN PHARMACEUTICA NV (BE) 2000-08-09 CN disclosed
US-4792635-A Symmetric benzophenones substituted by groups containing fluorine BAYER AKTIENGESELLSCHAFT (DE) 1988-12-20 US disclosed
EP-0156278-B1 PROCESS FOR THE PREPARATION OF SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS, THEIR USE AND SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS BAYER AG (DE) 1988-03-02 EP disclosed
EP-0156278-A2 Process for the preparation of symmetrical benzophenones substituted by fluor-containing groups, their use and symmetrical benzophenones substituted by fluor-containing groups BAYER AG (DE) 1985-10-02 EP disclosed