SCHEMBL31542016

SCHEMBL31542016

O=C(Cl)c1ccc(Cl)c(C(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.54
NPFFR2 Q9Y5X5 1/20 0.51
PDK1 Q15118 1/20 0.49
HSD11B1 P28845 1/20 0.47
HTR3E A5X5Y0 1/20 0.46
HTR3B O95264 1/20 0.46
HTR3A P46098 1/20 0.46
HTR3D Q70Z44 1/20 0.46
HTR3C Q8WXA8 1/20 0.46
SLC6A3 Q01959 1/20 0.44
PGR P06401 1/20 0.44
GRM4 Q14833 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
CHEK2 O96017 1/20 0.42
TRPV1 Q8NER1 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1794695 1.00 KDR (0.54) KDRNPFFR2PDK1HSD11B1HTR3E
SCHEMBL10656533 0.86 KDR (0.56) KDRNPFFR2PDK1HSD11B1HTR3E
SCHEMBL10532934 0.85 KMO (0.43) KDRPDK1NOTUM
SCHEMBL375961 0.85 TSHR (0.59) KDRNPFFR2PDK1HSD11B1HTR3E
SCHEMBL31542017 0.84 NOTUM (0.42) KDRNPFFR2HSD11B1MAPTNOTUM
SCHEMBL2680326 0.84 NOTUM (0.42) KDRNPFFR2HSD11B1MAPTNOTUM
Hydrochloric Acid SCHEMBL6369011 0.83 TSHR (0.57) KDRNPFFR2PDK1HSD11B1HTR3E
SCHEMBL31144967 0.83 NPFFR2 (0.58) KDRNPFFR2PDK1HSD11B1HTR3E
SCHEMBL1086197 0.83 NPFFR2 (0.58) KDRNPFFR2PDK1HSD11B1HTR3E
SCHEMBL76697 0.83 NPFFR2 (0.58) KDRNPFFR2PDK1HSD11B1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089403-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME 住友化学株式会社 2025-05-01 WO disclosed