SCHEMBL1065667

SCHEMBL1065667

C=CC(=O)OCC[Si](OC)(OC)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.51
TSHR P16473 7/20 0.40
HPGD P15428 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TP53 P04637 2/20 0.40
HIF1A Q16665 2/20 0.40
CYP3A4 P08684 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HCAR2 Q8TDS4 1/20 0.35
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33
THRA P10827 1/20 0.33
AKT1 P31749 2/20 0.33
MAPT P10636 1/20 0.33
ALOX5 P09917 1/20 0.32
TTR P02766 1/20 0.32
TGM2 P21980 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068326 0.92 THRB (0.49) THRBTSHRHPGDALDH1A1TP53
SCHEMBL7804589 0.90 THRB (0.48) THRBTSHRHPGDALDH1A1TP53
SCHEMBL21066664 0.89 TSHR (0.50) THRBTSHRHPGDALDH1A1TP53
SCHEMBL21174553 0.89 TSHR (0.50) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1066824 0.86 THRB (0.49) THRBTSHRHPGDALDH1A1TP53
SCHEMBL235466 0.85 THRB (0.46) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1066699 0.85 THRB (0.48) THRBTSHRHPGDALDH1A1TP53
SCHEMBL9402761 0.84 HCAR2 (0.40) ALDH1A1HCAR2AKR1B10AKR1B1AKT1
SCHEMBL29614542 0.81 THRB (0.57) THRBTSHRHPGDALDH1A1TP53
SCHEMBL21066825 0.80 TDP1 (0.46) TSHRHPGDALDH1A1TP53ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108300385-B Adhesive sheet, display, and method for producing same 琳得科株式会社 2022-02-15 CN disclosed
US-8829142-B2 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2014-09-09 US disclosed
EP-2270070-B1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO LTD (JP) 2014-07-30 EP disclosed
EP-2565217-B1 Curable composition and process for production of organosilicon compound TOAGOSEI CO LTD (JP) 2014-05-14 EP disclosed
US-20130149455-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2013-06-13 US disclosed
EP-2565217-A1 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2013-03-06 EP disclosed
US-20110071255-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2011-03-24 US disclosed
EP-2270070-A1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND Toagosei Co., Ltd (JP) 2011-01-05 EP disclosed