Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625213 | 0.90 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL19837219 | 0.82 | THRB (0.59) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL1065667 | 0.81 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL17373011 | 0.81 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10644010 | 0.81 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL1066824 | 0.79 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL11804363 | 0.79 | THRB (0.59) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL4661264 | 0.78 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL16788732 | 0.78 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL1066699 | 0.78 | THRB (0.48) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983461-A1 | SILYL-CONTAINING ACRYLATES AND DEGRADABLE RADICAL-CURED NETWORKS THEREOF | The Government of the United States of America, as represented by the Secretary of the Navy (US) | 2022-04-20 | — | — | EP | disclosed |