Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875178 | 0.82 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL7609997 | 0.79 | TSHR (0.39) | TSHRLMNAALDH1A1PDK2CYP2A6 | |
| SCHEMBL8489033 | 0.74 | TSHR (0.35) | TSHRLMNAALDH1A1PDK2CYP1A2 | |
| SCHEMBL7654371 | 0.72 | TSHR (0.47) | TSHRLMNAALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL28810873 | 0.71 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL3193352 | 0.71 | CYP3A4 (0.41) | TSHRALDH1A1PDK2KDM4EMAPT | |
| SCHEMBL10451589 | 0.71 | ALDH1A1 (0.41) | TSHRLMNAALDH1A1PDK2KDM4E | |
| SCHEMBL9240892 | 0.71 | TSHR (0.36) | TSHRLMNAALDH1A1PDK2KDM4E | |
| SCHEMBL6354181 | 0.71 | TSHR (0.53) | TSHRLMNAALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL11206197 | 0.70 | TSHR (0.45) | TSHRLMNAALDH1A1CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4731450-A | Process for perfluoroalkylation of aromatic derivatives | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-03-15 | — | — | US | disclosed |