Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656728 | 0.79 | TSHR (0.41) | TSHRLMNAALDH1A1PDK2CYP1A2 | |
| SCHEMBL10451332 | 0.76 | ALDH1A1 (0.36) | TSHRLMNAALDH1A1HSD11B1 | |
| SCHEMBL28344467 | 0.73 | TSHR (0.45) | TSHRLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27097039 | 0.73 | TSHR (0.45) | TSHRLMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11206197 | 0.73 | TSHR (0.45) | TSHRLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8489033 | 0.72 | TSHR (0.35) | TSHRLMNAALDH1A1PDK2CYP1A2 | |
| SCHEMBL8074942 | 0.72 | TSHR (0.35) | TSHRLMNA | |
| SCHEMBL174758 | 0.72 | TSHR (0.50) | TSHRLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27486616 | 0.70 | TSHR (0.47) | TSHRLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7654371 | 0.70 | TSHR (0.47) | TSHRLMNAALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726252-B1 | Process for the preparation of N-substituted cyclic imides | BAYER AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5773630-A | REACTION OF ANHYDRIDE WITH PRIMARY AMINE TO FORM CYCLIC IMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| EP-0726252-A1 | Process for the preparation of N-substituted cyclic imides | BAYER AG (DE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0527314-B1 | Process for the preparation of 2-aryl-2H-1,2,3-triazoles | LONZA AG (CH) | 1994-09-07 | — | — | EP | disclosed |
| US-5258523-A | Process for the production of 2-aryl-2H-1,2,3-triazoles | LONZA LTD. (CH) | 1993-11-02 | — | — | US | disclosed |
| EP-0527314-A1 | Process for the preparation of 2-aryl-2H-1,2,3-triazoles | LONZA AG (CH) | 1993-02-17 | — | — | EP | disclosed |