Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655172 | 0.84 | DGAT1 (0.38) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL10655856 | 0.84 | TDP1 (0.49) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL22123310 | 0.84 | DGAT1 (0.38) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL10658623 | 0.82 | DGAT1 (0.37) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL10628506 | 0.81 | MEN1 (0.38) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL10653727 | 0.80 | DGAT1 (0.40) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL10654838 | 0.79 | MAOA (0.40) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL28704683 | 0.75 | DGAT1 (0.41) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL28686649 | 0.75 | DGAT1 (0.41) | DGAT1CA12CA14CA1CA7 | |
| SCHEMBL27715395 | 0.70 | LMNA (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746649-A | Diamino acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1988-05-24 | — | — | US | disclosed |