Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ODC1 | P11926 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657241 | 0.73 | GRIK1 (0.42) | BLMSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL10657720 | 0.73 | GRIK1 (0.42) | BLMSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL10606428 | 0.60 | EPHX1 (0.34) | — | |
| SCHEMBL11849715 | 0.58 | ODC1 (0.43) | BLMMEN1CYP2D6TSHRNFKB1 | |
| SCHEMBL4081475 | 0.58 | SLC6A2 (0.37) | BLMSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL28099391 | 0.57 | MEN1 (0.43) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4970548 | 0.57 | TSHR (0.39) | BLMSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL349876 | 0.57 | THRB (0.54) | BLMSLC6A2SLC6A3MEN1CYP2D6 | |
| SCHEMBL11534069 | 0.55 | KMT2A (0.47) | BLMSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL11534068 | 0.55 | KMT2A (0.47) | BLMSLC6A2SLC6A4SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730006-A | BACTERICIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-08 | — | — | US | disclosed |