Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657364 | 1.00 | NR1D1 (0.52) | NR1D1NPSR1FKBP1APREPACE | |
| Hydrochloric Acid SCHEMBL10659176 | 0.87 | NR1D1 (0.52) | NR1D1NPSR1FKBP1APREPACE | |
| SCHEMBL10893958 | 0.86 | NPSR1 (0.53) | NR1D1NPSR1FKBP1APREPACE | |
| SCHEMBL11398579 | 0.86 | NPSR1 (0.53) | NR1D1NPSR1FKBP1APREPACE | |
| SCHEMBL29727828 | 0.83 | NPSR1 (0.53) | NR1D1NPSR1FKBP1AF10PTPN1 | |
| SCHEMBL8233145 | 0.83 | NPSR1 (0.53) | NR1D1NPSR1FKBP1AF10PTPN1 | |
| SCHEMBL5351382 | 0.82 | NPSR1 (0.48) | NR1D1NPSR1FKBP1APREPALDH1A1 | |
| Hydrochloric Acid SCHEMBL10657307 | 0.82 | NR1D1 (0.48) | NR1D1NPSR1FKBP1APREPACE | |
| SCHEMBL1049445 | 0.81 | NPSR1 (0.63) | NR1D1NPSR1PREPF10PTPN1 | |
| SCHEMBL14397408 | 0.80 | ACE (0.59) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762821-A | HYPOTENSIVES | SYNTEX (U.S.A.) INC. (US) | 1988-08-09 | — | — | US | disclosed |