Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10137577 | 0.85 | FKBP1A (0.47) | FKBP1AALDH1A1HPGD | |
| SCHEMBL16879293 | 0.85 | NR1D1 (0.59) | NR1D1MMP8MMP3MMP9MMP1 | |
| SCHEMBL10893958 | 0.83 | NPSR1 (0.53) | NPSR1NR1D1FKBP1AMMP8MMP3 | |
| SCHEMBL11398579 | 0.83 | NPSR1 (0.53) | NPSR1NR1D1FKBP1AMMP8MMP3 | |
| SCHEMBL10657364 | 0.82 | NR1D1 (0.52) | NPSR1NR1D1FKBP1APREPALDH1A1 | |
| SCHEMBL10657358 | 0.82 | NR1D1 (0.52) | NPSR1NR1D1FKBP1APREPALDH1A1 | |
| SCHEMBL23182808 | 0.81 | NPC1 (0.48) | FKBP1ATMEM97SIGMAR1 | |
| SCHEMBL8233145 | 0.80 | NPSR1 (0.53) | NPSR1NR1D1FKBP1A | |
| SCHEMBL29727828 | 0.80 | NPSR1 (0.53) | NPSR1NR1D1FKBP1A | |
| SCHEMBL13545530 | 0.80 | CHEK1 (0.46) | NR1D1MMP3MMP9MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |