⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662916 | 0.87 | KDM4E (0.34) | — | |
| SCHEMBL10658617 | 0.84 | TET2 (0.31) | — | |
| SCHEMBL10656370 | 0.75 | — | — | |
| SCHEMBL6063940 | 0.73 | KDM4E (0.34) | — | |
| SCHEMBL2405468 | 0.71 | — | — | |
| SCHEMBL4346127 | 0.71 | TET2 (0.32) | — | |
| SCHEMBL10952663 | 0.69 | KDM4E (0.32) | — | |
| SCHEMBL6063482 | 0.69 | KDM4E (0.41) | — | |
| SCHEMBL1735212 | 0.68 | PKM (0.35) | — | |
| SCHEMBL4930948 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743667-A | ACRYLATED SILOXXANES, OXYGEN PERMEABLE | NIPPON CONTACT LENS, INC. (JP) | 1988-05-10 | — | — | US | disclosed |
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | disclosed |