SCHEMBL6063940

SCHEMBL6063940

C=C(C(=O)O)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL5866009 0.90 LMNA (0.39)
SCHEMBL6063482 0.86 KDM4E (0.41) KDM4ETSHRTDP1
SCHEMBL6062455 0.82
SCHEMBL10952663 0.77 KDM4E (0.32) KDM4ETSHRTDP1
SCHEMBL339831 0.77
SCHEMBL1735212 0.75 PKM (0.35)
SCHEMBL1259986 0.74 THRB (0.42) KDM4ETSHRTDP1
SCHEMBL1416716 0.74 TET2 (0.38)
SCHEMBL9546053 0.73 THRB (0.30)
SCHEMBL10657428 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250616-A4 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INC (US) 2005-09-28 EP claimed
US-6577787-B2 Tuning of optical waveguide devices containing an organic material CORNING INCORPORATED 2003-06-10 US claimed
US-20030081876-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED 2003-05-01 US claimed
EP-1250616-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED (US) 2002-10-23 EP claimed
US-20010016093-A1 Athermalized integrated optical waveguide devices LUMENTUM OPTICS INC. 2001-08-23 US claimed
EP-1118886-A1 Tuning of optical waveguide devices containing an organic material CORNING INCORPORATED (US) 2001-07-25 EP claimed
WO-2001051969-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED (US) 2001-07-19 WO claimed
WO-2001051967-A1 ATHERMALIZED INTEGRATED OPTICAL WAVEGUIDE DEVICES CORNING INCORPORATED (US) 2001-07-19 WO claimed
EP-1116973-A1 Athermalized integrated optical waveguide devices Corning Incorporated (US) 2001-07-18 EP claimed
US-7148363-B2 Process for preparing acrylate compound TOSOH CORPORATION (JP) 2006-12-12 US disclosed
EP-1250616-A4 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INC (US) 2005-09-28 EP disclosed
US-20050148789-A1 Process for preparing acrylate compound TOSOH CORPORATION 2005-07-07 US disclosed
US-6833462-B2 Esterification to get cyclic acrylate compounds; used as raw material for functional polymers, pharmaceuticals, pesticides, semiconductor lithography TOSOH CORPORATION (JP) 2004-12-21 US disclosed
US-20030139613-A1 Process for preparing acrylate compound TOSOH CORPORATION 2003-07-24 US disclosed
EP-1250616-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED (US) 2002-10-23 EP disclosed
US-20010016093-A1 Athermalized integrated optical waveguide devices LUMENTUM OPTICS INC. 2001-08-23 US disclosed
EP-1118886-A1 Tuning of optical waveguide devices containing an organic material CORNING INCORPORATED (US) 2001-07-25 EP disclosed
WO-2001051969-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED (US) 2001-07-19 WO disclosed
WO-2001051967-A1 ATHERMALIZED INTEGRATED OPTICAL WAVEGUIDE DEVICES CORNING INCORPORATED (US) 2001-07-19 WO disclosed
EP-1116973-A1 Athermalized integrated optical waveguide devices Corning Incorporated (US) 2001-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139613-A1 Process for preparing acrylate compound AFF1, AFF4, RER1 KDM4E 1056/4885TSHR 994/4885TDP1 3679/4885
US-20050148789-A1 Process for preparing acrylate compound ACR, AFF4, AFF1 KDM4E 1224/4885TSHR 418/4885TDP1 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.