SCHEMBL1065756

SCHEMBL1065756

FC(F)(F)c1cccc([C]2CC2)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.53
ASIC3 Q9UHC3 1/20 0.50
KDM1A O60341 1/20 0.49
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
NOTUM Q6P988 2/20 0.47
IDO1 P14902 1/20 0.47
PARP10 Q53GL7 1/20 0.46
PARP11 Q9NR21 1/20 0.46
SCN2A Q99250 2/20 0.46
MAOB P27338 1/20 0.46
GALR1 P47211 1/20 0.45
CTSS P25774 1/20 0.45
CES2 O00748 1/20 0.44
MGLL Q99685 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2532289 0.92 HTR2C (0.50) HTR2CASIC3KDM1ATSHRMAPK1
SCHEMBL8689815 0.87 HTR2C (0.62) HTR2CASIC3KDM1AIDO1PARP10
SCHEMBL1263144 0.84 TSHR (0.58) HTR2CASIC3KDM1ATSHRMAPK1
SCHEMBL29678302 0.84 TSHR (0.58) HTR2CASIC3KDM1ATSHRMAPK1
Ammonia Solution, Strong SCHEMBL20472961 0.81 MAOB (0.56) HTR2CASIC3KDM1ATSHRMAPK1
SCHEMBL14893807 0.80 KDM1A (0.49) HTR2CASIC3KDM1ATSHRMAPK1
SCHEMBL8349987 0.80 ASIC3 (0.64) HTR2CASIC3KDM1AIDO1PARP10
SCHEMBL307920 0.77 KIF11 (0.62) ASIC3KDM1ATSHRMAPK1NOTUM
SCHEMBL29420699 0.77 KIF11 (0.62) ASIC3KDM1ATSHRMAPK1NOTUM
SCHEMBL26827704 0.77 MAOB (0.62) ASIC3KDM1ATSHRMAPK1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014029708-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029707-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029706-A2 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029710-A2 METHODS OF SOIL PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014019609-A1 METHODS OF PEST CONTROL IN SOYBEAN SYNGENTA PARTICIPATIONS AG (CH) 2014-02-06 WO disclosed
EP-2277869-A1 Cycloalkylamidbenzoxa(thia)zoles as fungicides Bayer CropScience AG (DE) 2011-01-26 EP disclosed
EP-0832073-B1 QUINAZOLINES AND PHARMACEUTICAL COMPOSITIONS SUGEN INC (US) 2002-01-16 EP disclosed
US-5051447-A Applying aromatic oximes to plants, seeds or soils BASF AKTIENGESELLSCHAFT (DE) 1991-09-24 US disclosed
US-4952720-A Ortho-substituted benzyl carboxylates and fungicides which contain these compounds BASF AKTIENGSELLSCHAFT (DE) 1990-08-28 US disclosed