Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.35 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19152684 | 0.78 | CYP19A1 (0.39) | MAPTNPC1TP53HTTRAB9A | |
| SCHEMBL230331 | 0.72 | F12 (0.59) | PRNPMAPTNPC1HTTRAB9A | |
| Hydrochlorthiazide SCHEMBL9107872 | 0.69 | F12 (0.42) | PRNPMAPTNPC1TP53HTT | |
| SCHEMBL18238487 | 0.67 | CNR2 (0.38) | MAPTNPC1TP53HTTRAB9A | |
| SCHEMBL1609661 | 0.65 | ADORA3 (0.54) | NFATC1GSK3BDYRK1AATMADORA3 | |
| SCHEMBL11778954 | 0.64 | RAB9A (0.50) | PRNPMAPTNPC1TP53RAB9A | |
| SCHEMBL16608503 | 0.63 | IDO1 (0.38) | MAPTNPC1TP53HTTRAB9A | |
| SCHEMBL19153567 | 0.63 | CYP19A1 (0.42) | MAPTNPC1TP53HTTRAB9A | |
| SCHEMBL3483139 | 0.63 | PRNP (0.37) | PRNPMAPTF12GAA | |
| SCHEMBL11781952 | 0.61 | ALDH1A1 (0.66) | MAPTNPC1TP53HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786633-A | HIGHER ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0248645-A2 | Cephalosporin compounds | Tanabe Seiyaku Co., Ltd. (JP) | 1987-12-09 | — | — | EP | disclosed |