Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657934 | 1.00 | NOD1 (0.55) | NOD1LPAR3SLC6A5MEN1FAAH | |
| SCHEMBL5529716 | 0.84 | PSMB5 (0.44) | NOD1LPAR3 | |
| SCHEMBL4627107 | 0.82 | NOD1 (0.62) | NOD1SLC6A5MEN1FAAHMAPK1 | |
| SCHEMBL9652260 | 0.80 | NOD1 (0.60) | NOD1SLC6A5MEN1FAAHMAPK1 | |
| SCHEMBL9831556 | 0.80 | NOD1 (0.75) | NOD1SLC6A5 | |
| SCHEMBL9831553 | 0.80 | NOD1 (0.75) | NOD1SLC6A5 | |
| SCHEMBL31720996 | 0.80 | NOD1 (0.60) | NOD1SLC6A5MEN1FAAHMAPK1 | |
| SCHEMBL10064044 | 0.80 | DNM1 (0.51) | LPAR3MEN1FAAHMAPK1KMT2A | |
| SCHEMBL9829528 | 0.80 | NOD1 (0.70) | NOD1SLC6A5MEN1FAAHMAPK1 | |
| SCHEMBL9829527 | 0.80 | NOD1 (0.70) | NOD1SLC6A5MEN1FAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |