Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947889 | 0.86 | AAK1 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10876285 | 0.83 | MEN1 (0.58) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL11640367 | 0.78 | CYP1A2 (0.59) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL6262245 | 0.77 | MEN1 (0.49) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL10657866 | 0.76 | ACP1 (0.54) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL15541859 | 0.74 | SMN1; SMN2 (0.59) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL10305757 | 0.74 | SIRT2 (0.47) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL15828841 | 0.72 | ALOX5 (0.46) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL7685160 | 0.72 | ALDH1A1 (0.60) | KMT2AMAPTMEN1HTTLMNA | |
| SCHEMBL7833515 | 0.72 | SMN1; SMN2 (0.69) | KMT2AMAPTMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725620-A | 2H-pyran-2,6-(3H)-dione derivatives with anti-allergic activity | ALLERGAN, INC. (US) | 1988-02-16 | — | — | US | disclosed |