Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | USP2 | O75604 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 6/20 | 0.38 |
| ▸ | CASP7 | P55210 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378398 | 0.93 | CYP1A2 (0.41) | ALDH1A1CYP3A4CYP1A2LMNAKMT2A | |
| SCHEMBL10653938 | 0.88 | EPHB4 (0.52) | ALDH1A1CYP1A2LMNAPOLBHSD17B10 | |
| SCHEMBL10654481 | 0.87 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP1A2LMNAKMT2A | |
| SCHEMBL10659366 | 0.85 | GABRA1 (0.36) | ALDH1A1CYP3A4CYP1A2KMT2AMEN1 | |
| SCHEMBL10655567 | 0.85 | GABRA1 (0.36) | ALDH1A1CYP3A4CYP1A2KMT2AMEN1 | |
| SCHEMBL10661938 | 0.85 | PDE4A (0.38) | ALDH1A1CYP3A4CYP1A2KMT2AMEN1 | |
| SCHEMBL9629703 | 0.85 | PKM (0.45) | ALDH1A1CYP3A4CYP1A2LMNAKMT2A | |
| SCHEMBL10377181 | 0.81 | EPHB4 (0.48) | CYP1A2LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL10378419 | 0.80 | ALDH1A1 (0.36) | ALDH1A1CYP1A2LMNAKMT2AMEN1 | |
| SCHEMBL10654535 | 0.79 | PKM (0.42) | ALDH1A1CYP3A4CYP1A2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740511-A | ANTIALLERGENS, ANTIINFLAMMATORY, ANTIULCER AGENTS | SCHERING CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| US-4680298-A | Tricyclic anti-allergy and use as anti-inflammatory agents | SCHERING CORPORATION (US) | 1987-07-14 | — | — | US | disclosed |
| US-4680297-A | Tricyclic positive inotropic agents | SCHERING CORPORATION (US) | 1987-07-14 | — | — | US | disclosed |