Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277432 | 0.85 | RAB9A (0.70) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL750529 | 0.84 | KCNK3 (0.59) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| N-(Phenylcarbamothioyl)Benzamide SCHEMBL2341910 | 0.84 | EPHX1 (1.00) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL8616503 | 0.76 | EPHX1 (0.83) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29971986 | 0.76 | RAB9A (0.86) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL16918559 | 0.76 | RAB9A (0.86) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL31321777 | 0.75 | ALDH1A1 (0.85) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL27451748 | 0.75 | MIF (0.83) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11167105 | 0.75 | RAB9A (0.80) | EPHX1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL750970 | 0.74 | SIRT1 (0.58) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766213-A | 1,4-dihydropyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-08-23 | — | — | US | disclosed |