SCHEMBL10658904

SCHEMBL10658904

C=CC(=O)NC1CCCCN1C(=O)C=C

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.38
CYP3A4 P08684 1/20 0.36
TEAD1 P28347 5/20 0.34
TGM2 P21980 4/20 0.33
HTT P42858 1/20 0.33
F13A1 P00488 2/20 0.32
TGM1 P22735 2/20 0.32
JAK3 P52333 1/20 0.31
MAPK1 P28482 1/20 0.30
BTK Q06187 1/20 0.30
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19890684 0.76 SRC (0.42) SRCCYP3A4JAK3MAPK1BTK
SCHEMBL29963478 0.73 TEAD1 (0.35) TEAD1TGM2HTTMAPK1
SCHEMBL7857359 0.73 SRC (0.42) SRCJAK3MAPK1BTK
SCHEMBL20399511 0.73 SRC (0.42) SRCJAK3MAPK1BTK
SCHEMBL28065540 0.72 TEAD1 (0.38) CYP3A4TEAD1TGM2JAK3MAPK1
SCHEMBL23221995 0.72 HPGD (0.51) SRCMAPK1SMN1; SMN2
SCHEMBL15049184 0.72 HPGD (0.51) SRCMAPK1SMN1; SMN2
SCHEMBL23080317 0.72 HPGD (0.51) SRCMAPK1SMN1; SMN2
SCHEMBL21075876 0.72 SRC (0.41) SRCJAK3MAPK1BTK
SCHEMBL21075772 0.72 SRC (0.41) SRCJAK3MAPK1BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4729834-A ACRYLIC AMIDE POLYMERS MITSUI TOATSU CHEMICALS, INC. (JP) 1988-03-08 US disclosed