Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459414 | 0.77 | UCHL3 (0.34) | TEAD1TSHRMEN1KMT2A | |
| SCHEMBL14076271 | 0.77 | CA1 (0.40) | ALDH1A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL10658904 | 0.72 | SRC (0.38) | TEAD1MAPK1BTKCYP3A4KDM4E | |
| SCHEMBL16791394 | 0.72 | BTK (0.42) | TEAD1ALDH1A1BTKKDM4E | |
| SCHEMBL19826021 | 0.72 | BTK (0.42) | TEAD1ALDH1A1BTKKDM4E | |
| SCHEMBL16127672 | 0.72 | BTK (0.42) | TEAD1ALDH1A1BTKKDM4E | |
| SCHEMBL10520187 | 0.72 | HTT (0.37) | ALDH1A1KDM4E | |
| SCHEMBL24492178 | 0.71 | ALDH1A1 (0.42) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL16078850 | 0.71 | ALDH1A1 (0.42) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL8571021 | 0.70 | HTT (0.36) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109647232-B | Method for preparing cobalt (II) ion imprinting composite membrane by using N-methylpyrrolidine acrylamide | 昆明理工大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-103987700-B | 4-quinazoline amine derivant and application thereof | 江苏豪森药业集团有限公司 | 2016-08-31 | — | — | CN | disclosed |