SCHEMBL349876

SCHEMBL349876

NC(CCC(=O)O)(C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.54
KMT2A Q03164 3/20 0.54
ALDH1A1 P00352 3/20 0.54
CYP1A2 P05177 2/20 0.54
MEN1 O00255 2/20 0.54
LMNA P02545 5/20 0.42
ALKBH5 Q6P6C2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
NAALAD2 Q9Y3Q0 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.38
HIF1A Q16665 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 4/20 0.38
GABRR1 P24046 2/20 0.38
HDAC3 O15379 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
BLM P54132 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11037692 0.85 ALDH1A1 (0.52) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL28500432 0.85 ALDH1A1 (0.52) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL11211091 0.84 THRB (0.45) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL28957144 0.82 CYP1A2 (0.44) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL8232146 0.80 TSHR (0.55) THRBKMT2AALDH1A1MEN1LMNA
SCHEMBL31282824 0.80 ALDH1A1 (0.52) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL9586044 0.78 CYP1A2 (0.74) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL497168 0.78 THRB (0.54) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL3185113 0.77 THRB (0.43) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL8751907 0.77 ALDH1A1 (0.44) THRBKMT2AALDH1A1CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4853220-A Protein isolated from blood, process for preparing said protein, aantibodies against said new protein, and pharmaceutical compositions containing said protein or said antibodies NEDERLANDSE CENTRALE ORGANISATIE VOOR TOEGERASTNATUURWETE NSCHAPPELIJK ONDERZOEK (NL) 1989-08-01 US claimed
EP-4719381-A1 LIGAND-POLAR DRUG CONJUGATES Tripartite Therapeutics Inc. (TW) 2026-04-08 EP disclosed
US-12540946-B2 Methods and systems for detecting and quantifying large number of molecule biomarkers from a body fluid sample COMPLETE OMICS INC. (US) 2026-02-03 US disclosed
EP-4634392-A1 MODIFIED HERPES SIMPLEX VIRUS TYPE 1 EG 427 (FR) 2025-10-22 EP disclosed
EP-4630547-A1 VIRAL VECTOR ENCODING GAD FOR TREATING SPASTICITY EG 427 (FR) 2025-10-15 EP disclosed
EP-4627079-A2 THERMOSTABLE BINDING SCAFFOLDS Nectagen, Inc. (US) 2025-10-08 EP disclosed
EP-4626489-A1 PCTA DERIVATIVES, CONJUGATES THEREOF AND USES THEREOF Novartis AG (CH) 2025-10-08 EP disclosed
EP-4551563-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-05-14 EP disclosed
CN-119816487-A FC conjugates comprising CD73 inhibitors and uses thereof 奇达拉治疗公司 2025-04-11 CN disclosed
WO-2025064788-A2 CCR5 CONJUGATES AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-03-27 WO disclosed
EP-0625988-A4 ALLOSTERIC MODULATORS OF THE NMDA RECEPTOR. MACCECCHINI MARIA LUISA (US) 1998-03-04 EP disclosed
WO-1998000443-A1 THROMBIN INHIBITORS TRIGEN LIMITED (GB) 1998-01-08 WO disclosed
EP-0809650-A1 SERINE PROTEASE INHIBITORS ELLERMAN PHARMACEUTICALS LIMITED (GB) 1997-12-03 EP disclosed
US-5610278-A Process for producing a coagulation active complex of factor VIII fragments NOVO NORDISK A/S (DK) 1997-03-11 US disclosed
WO-1996025427-A1 SERINE PROTEASE INHIBITORS ELLERMAN PHARMACEUTICALS LIMITED (GB) 1996-08-22 WO disclosed
US-5460835-A Aluminum salts in the treatment of bone disease DUKE UNIVERSITY (US) 1995-10-24 US disclosed
EP-0625988-A1 ALLOSTERIC MODULATORS OF THE NMDA RECEPTOR MACCECCHINI, Maria-Luisa (US) 1994-11-30 EP disclosed
WO-1994007914-A1 ALLOSTERIC MODULATORS OF THE NMDA RECEPTOR MACCECCHINI MARIA LUISA (US) 1994-04-14 WO disclosed
US-5019401-A Aluminum salts in the treatment of bone disease DUKE UNIVERSITY (US) 1991-05-28 US disclosed
US-4149936-A IMMOBILIZED CELLS CORNING GLASS WORKS (US) 1979-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540946-B2 Methods and systems for detecting and quantifying large number of molecule biomarkers from a body fluid sample MYADM, EPCAM, CD14 THRB 568/4885KMT2A 3845/4885ALDH1A1 1768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.