Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474509 | 0.93 | TSHR (0.39) | TSHRSLC22A6TDP1GPR84ALDH1A1 | |
| SCHEMBL6829382 | 0.91 | GPR84 (0.39) | TSHRSLC22A6TDP1GPR84ALDH1A1 | |
| SCHEMBL4844058 | 0.81 | LMNA (0.46) | TSHRSLC22A6GPR84FOLH1GABRR1 | |
| SCHEMBL28099127 | 0.79 | SLC22A6 (0.35) | TSHRSLC22A6TDP1GPR84SMN1; SMN2 | |
| SCHEMBL6464981 | 0.79 | GPR84 (0.50) | TSHRSLC22A6TDP1GPR84ALDH1A1 | |
| SCHEMBL23829834 | 0.79 | LMNA (0.43) | TSHRSLC22A6GPR84FOLH1GABRR1 | |
| SCHEMBL6463034 | 0.77 | GPR84 (0.59) | TSHRSLC22A6TDP1GPR84ALDH1A1 | |
| SCHEMBL6460749 | 0.77 | BLM (0.45) | SLC22A6GPR84LMNALCKPPARD | |
| SCHEMBL6465807 | 0.77 | BLM (0.41) | SLC22A6GPR84LMNALCKPPARD | |
| SCHEMBL666360 | 0.76 | GPR84 (0.57) | TSHRSLC22A6TDP1GPR84SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| EP-0090516-B1 | SUBSTITUTED HEXAHYDROPYRROLO(1,2-A)-QUINOLINE, HEXAHYDRO-1H-PYRIDO(1,2-A)-QUINOLINE, HEXAHYDROBENZO(3)INDENE AND OCTAHYDROPHENANTHRENE CNS AGENTS | PFIZER INC. (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4576964-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1986-03-18 | — | — | US | disclosed |
| US-4476131-A | ANTIEMETICS, ANALGESICS | PFIZER INC. (US) | 1984-10-09 | — | — | US | disclosed |
| EP-0090516-A1 | Substituted hexahydropyrrolo(1,2-a)-quinoline, hexahydro-1H-pyrido(1,2-a)-quinoline, hexahydrobenzo(3)indene and octahydrophenanthrene CNS agents | PFIZER INC. (US) | 1983-10-05 | — | — | EP | disclosed |