Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 12/20 | 0.66 |
| ▸ | ATP4B | P51164 | 12/20 | 0.66 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661906 | 0.89 | ATP4A (0.67) | ATP4AATP4BALDH1A1MAPTPTGDR2 | |
| SCHEMBL10571329 | 0.81 | ATP4A (0.64) | ATP4AATP4BALDH1A1GAAMAPT | |
| SCHEMBL10656397 | 0.80 | ATP4A (0.65) | ATP4AATP4B | |
| SCHEMBL10659756 | 0.79 | ATP4A (1.00) | ATP4AATP4B | |
| SCHEMBL12696805 | 0.76 | LTA4H (0.41) | MAPT | |
| SCHEMBL7674368 | 0.74 | NPC1 (0.49) | HRH3ALDH1A1MAPTRAB9A | |
| SCHEMBL7686736 | 0.73 | ATP4A (0.60) | ATP4AATP4BALDH1A1GAAMAPT | |
| SCHEMBL10660395 | 0.73 | ATP4A (0.65) | ATP4AATP4BRAB9A | |
| SCHEMBL10662353 | 0.73 | ATP4A (0.61) | ATP4AATP4BMAPTRAB9A | |
| SCHEMBL10656918 | 0.72 | ATP4A (0.62) | ATP4AATP4BALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791200-A | ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-12-13 | — | — | US | claimed |
| US-4791200-A | ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |