Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574601 | 0.75 | KDM4E (0.44) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL1226226 | 0.75 | GRIA1 (0.60) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL11098374 | 0.73 | LMNA (0.46) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL27831324 | 0.72 | LMNA (0.45) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL9481857 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL17897700 | 0.72 | LMNA (0.54) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL27744847 | 0.70 | LMNA (0.46) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL21465946 | 0.70 | LMNA (0.56) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL27538958 | 0.70 | LMNA (0.52) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL14478236 | 0.69 | GRIA1 (0.66) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265506-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1988-05-04 | — | — | EP | claimed |
| WO-1987006581-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1987-11-05 | — | — | WO | claimed |