Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719842 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2HPGDDAOALDH1A1KDM4E | |
| SCHEMBL5115615 | 0.76 | HPGD (0.67) | HPGDDAOKDM4ECYP1A2GRIA1 | |
| SCHEMBL11315735 | 0.75 | HPGD (0.65) | HPGDDAOKDM4ECYP1A2GRIA1 | |
| Hydrogen Sulfide SCHEMBL27583640 | 0.75 | HPGD (0.65) | HPGDDAOKDM4ECYP1A2GRIA1 | |
| SCHEMBL27574601 | 0.73 | KDM4E (0.44) | SMN1; SMN2HPGDALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10660016 | 0.72 | LMNA (0.49) | SMN1; SMN2ALDH1A1KDM4ECYP1A2GRIA1 | |
| SCHEMBL28749557 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL15760446 | 0.71 | LMNA (0.52) | SMN1; SMN2HPGDDAOALDH1A1KDM4E | |
| SCHEMBL9652245 | 0.71 | ALDH1A1 (0.43) | SMN1; SMN2HPGDDAOALDH1A1KDM4E | |
| SCHEMBL599993 | 0.69 | HSP90AA1 (0.41) | SMN1; SMN2ALDH1A1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |