Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667312 | 0.89 | POLB (0.51) | L3MBTL1TP53MEN1KMT2APOLB | |
| SCHEMBL10662501 | 0.88 | SHMT2 (0.45) | TSHRL3MBTL1POLBLMNASHMT2 | |
| SCHEMBL10669664 | 0.87 | MAPT (0.54) | TSHRL3MBTL1TP53POLB | |
| SCHEMBL10667697 | 0.86 | POLB (0.42) | L3MBTL1TP53POLB | |
| SCHEMBL10668567 | 0.85 | POLB (0.47) | L3MBTL1TP53POLB | |
| SCHEMBL10662031 | 0.85 | POLB (0.44) | L3MBTL1TP53POLB | |
| SCHEMBL10667350 | 0.83 | POLB (0.46) | TSHRL3MBTL1TP53POLBLMNA | |
| SCHEMBL10660555 | 0.82 | ALDH1A1 (0.49) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL10667655 | 0.81 | ATM (0.50) | L3MBTL1TP53KMT2APOLB | |
| SCHEMBL10662720 | 0.80 | POLB (0.42) | TSHRL3MBTL1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63162681-A | — | — | None | — | — | JP | disclosed |
| US-4780462-A | Antihypertensive 1,5-benzothiazepine derivatives and compositions thereof | Kotokuki Seiya Kau Co., Ltd. (JP) | 1988-10-25 | — | — | US | disclosed |
| JP-S63162681-A | 1,5-BENZOTHIAZEPINE DERIVATIVE, HYPOTENSOR AND PRODUCTION THEREOF | KOTOBUKI SEIYAKU KK | 1988-07-06 | — | — | JP | disclosed |