Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667312 | 0.88 | POLB (0.51) | POLBL3MBTL1DRD4TP53MAPT | |
| SCHEMBL10661968 | 0.86 | TSHR (0.46) | POLBL3MBTL1TP53 | |
| SCHEMBL10668567 | 0.84 | POLB (0.47) | POLBL3MBTL1DRD4TP53MAPT | |
| SCHEMBL10669664 | 0.82 | MAPT (0.54) | POLBL3MBTL1DRD4TP53MAPT | |
| SCHEMBL10667350 | 0.82 | POLB (0.46) | POLBL3MBTL1DRD4TP53MAPT | |
| SCHEMBL10660555 | 0.81 | ALDH1A1 (0.49) | POLBDRD4MAPT | |
| SCHEMBL10662031 | 0.80 | POLB (0.44) | POLBL3MBTL1DRD4TP53MAPT | |
| SCHEMBL10662501 | 0.80 | SHMT2 (0.45) | POLBL3MBTL1MAPT | |
| SCHEMBL10662720 | 0.80 | POLB (0.42) | POLBL3MBTL1DRD4TP53MAPT | |
| SCHEMBL10482981 | 0.78 | POLB (0.39) | POLBL3MBTL1DRD4TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780462-A | Antihypertensive 1,5-benzothiazepine derivatives and compositions thereof | Kotokuki Seiya Kau Co., Ltd. (JP) | 1988-10-25 | — | — | US | disclosed |