Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661986 | 1.00 | SRD5A2 (0.62) | SRD5A2TBXAS1THRBATMNPC1 | |
| SCHEMBL1006525 | 0.84 | SRD5A2 (0.84) | SRD5A2THRBATMNPC1RAB9A | |
| SCHEMBL1711041 | 0.84 | SRD5A2 (0.84) | SRD5A2THRBATMNPC1RAB9A | |
| SCHEMBL9836849 | 0.83 | TBXAS1 (0.53) | SRD5A2TBXAS1NPC1RAB9AALDH1A1 | |
| SCHEMBL9836844 | 0.83 | TBXAS1 (0.53) | SRD5A2TBXAS1NPC1RAB9AALDH1A1 | |
| Methane SCHEMBL9562938 | 0.82 | SRD5A2 (0.81) | SRD5A2THRBATMNPC1RAB9A | |
| SCHEMBL10416058 | 0.79 | KDM4E (0.63) | RAB9AMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10416059 | 0.79 | KDM4E (0.63) | RAB9AMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL22510821 | 0.79 | KMT2A (0.71) | TBXAS1THRBATMLMNAMEN1 | |
| SCHEMBL15177166 | 0.78 | LMNA (0.53) | NPC1RAB9ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496735-A | THROMBOXANE A2 INHIBITOR | MARUKO SEIYAKU CO., LTD. (JP) | 1985-01-29 | — | — | US | claimed |
| US-4731370-A | VASODILATOR, ANTICOAGULANT | TOYAMA CHEMICAL CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| US-4713387-A | Vasodilating and platelet aggregation inhibiting 1,4 dihydropyridines with an imidazolyl or pyridyl containing ester | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
| US-4496735-A | THROMBOXANE A2 INHIBITOR | MARUKO SEIYAKU CO., LTD. (JP) | 1985-01-29 | — | — | US | disclosed |