Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836849 | 1.00 | TBXAS1 (0.53) | TBXAS1MAPTKMT2AP4HTMRAB9A | |
| SCHEMBL3179345 | 0.88 | SRD5A2 (0.56) | KMT2AP4HTMRAB9ANPC1KDM4E | |
| SCHEMBL3179354 | 0.88 | SRD5A2 (0.56) | KMT2AP4HTMRAB9ANPC1KDM4E | |
| SCHEMBL10661997 | 0.83 | SRD5A2 (0.62) | TBXAS1MAPTKMT2ARAB9ANPC1 | |
| SCHEMBL10661986 | 0.83 | SRD5A2 (0.62) | TBXAS1MAPTKMT2ARAB9ANPC1 | |
| SCHEMBL510617 | 0.80 | ALDH1A1 (0.59) | MAPTKMT2ARAB9ANPC1MAPK1 | |
| SCHEMBL9835980 | 0.80 | RHOA (0.53) | KMT2AP4HTMRAB9ANPC1KDM4E | |
| SCHEMBL9835977 | 0.80 | RHOA (0.53) | KMT2AP4HTMRAB9ANPC1KDM4E | |
| SCHEMBL3618165 | 0.78 | ALDH1A1 (0.65) | KMT2AP4HTMRAB9ANPC1KDM4E | |
| SCHEMBL3618167 | 0.78 | ALDH1A1 (0.65) | KMT2AP4HTMRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210782-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| US-4778796-A | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0210782-A2 | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-02-04 | — | — | EP | disclosed |