Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668067 | 0.91 | ADRB2 (0.43) | ADRB2ADRB1ADRB3ALDH1A1MEN1 | |
| SCHEMBL10667143 | 0.90 | HIF1A (0.49) | ADRB2ADRB1ADRB3ALDH1A1MEN1 | |
| SCHEMBL5605106 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11230234 | 0.81 | ADRB1 (0.66) | ADRB2ADRB1ADRB3ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL11247359 | 0.80 | ADRB1 (0.68) | ADRB2ADRB1ADRB3ALDH1A1MEN1 | |
| SCHEMBL10663547 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11743087 | 0.77 | MEN1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11164763 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8975021 | 0.76 | MAPT (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL18138767 | 0.75 | MAPT (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721717-A | α-(aminoalkylaminomethyl)phenylmethanols, composition containing them, and use thereof to treat certain heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-01-26 | — | — | US | disclosed |
| EP-0171689-B1 | AMINOALCOHOLS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS AND INTERMEDIATES | Roche Diagnostics GmbH (DE) | 1987-11-11 | — | — | EP | disclosed |
| EP-0171689-A1 | Aminoalcohols, process for their preparation and medicaments containing these compounds and intermediates | Roche Diagnostics GmbH (DE) | 1986-02-19 | — | — | EP | disclosed |