Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985654 | 0.80 | CYP19A1 (0.54) | CYP19A1CYP3A4CYP3A5ALDH1A1KDM4E | |
| SCHEMBL7417577 | 0.79 | CYP19A1 (0.47) | CYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL10989469 | 0.77 | CYP19A1 (0.51) | CYP19A1CYP3A4CYP3A5ALDH1A1KDM4E | |
| SCHEMBL27497680 | 0.69 | CYP19A1 (0.55) | CYP19A1CYP3A4CYP3A5SMN1; SMN2CCR1 | |
| SCHEMBL10806187 | 0.69 | CYP19A1 (0.51) | CYP19A1CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL28458232 | 0.68 | GAA (0.38) | ALDH1A1KDM4E | |
| SCHEMBL10559448 | 0.68 | ALDH1A1 (0.48) | CYP19A1CYP3A4CYP3A5ALDH1A1KDM4E | |
| SCHEMBL10674497 | 0.67 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5SMN1; SMN2 | |
| SCHEMBL9314550 | 0.67 | CYP19A1 (0.51) | CYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL6216972 | 0.67 | CYP19A1 (0.51) | CYP19A1CYP3A4ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743603-A | SCLEROTINIACEAE | RHONE-POULENC AGROCHIMIE (FR) | 1988-05-10 | — | — | US | disclosed |