Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999341 | 0.82 | CFTR (0.44) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10664321 | 0.79 | CYP19A1 (0.49) | CYP19A1SMN1; SMN2KDM4E | |
| SCHEMBL1275688 | 0.77 | TRPA1 (0.46) | SMN1; SMN2KDM4E | |
| SCHEMBL3447644 | 0.77 | TRPA1 (0.46) | SMN1; SMN2KDM4E | |
| SCHEMBL9314550 | 0.76 | CYP19A1 (0.51) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17591685 | 0.75 | CFTR (0.52) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7021489 | 0.75 | CYP19A1 (0.55) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27929742 | 0.74 | OPRM1 (0.52) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| Hydrochloric Acid SCHEMBL1477644 | 0.73 | MEN1 (0.37) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6581568 | 0.73 | CFTR (0.50) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994373-A | COGNITION ACTIVATORS; GASTROINTESTINAL DISORDERS; PSYCHOLOGICAL DISORDERS | NOVO NORDISK A/S NOVO ALLE DK 2880 (DK) | 1999-11-30 | — | — | US | disclosed |
| EP-0835255-A1 | NOVEL SUBSTITUTED AZACYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001555-A1 | NOVEL SUBSTITUTED AZACYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-01-16 | — | — | WO | disclosed |