Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 12/20 | 0.36 |
| ▸ | PPARG | P37231 | 12/20 | 0.36 |
| ▸ | PPARD | Q03181 | 12/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735554 | 0.89 | NPC1 (0.35) | PPARAPPARGPPARDNPC1HTT | |
| SCHEMBL10735335 | 0.89 | TP53 (0.37) | ALOX5APFEN1PPARAPPARGPPARD | |
| SCHEMBL10661817 | 0.86 | FFAR4 (0.41) | ALOX5APFEN1PPARAPPARGPPARD | |
| Brocrinat SCHEMBL29452050 | 0.84 | PPARG (0.43) | ALOX5APFEN1PPARAPPARGPPARD | |
| Brocrinat SCHEMBL636178 | 0.84 | PPARG (0.43) | ALOX5APFEN1PPARAPPARGPPARD | |
| SCHEMBL10730700 | 0.82 | RAB9A (0.49) | NPC1 | |
| SCHEMBL10662293 | 0.82 | KCNN4 (0.38) | ALOX5APFEN1NPC1HTT | |
| SCHEMBL10659946 | 0.82 | FHIT (0.48) | NPC1 | |
| SCHEMBL10659998 | 0.81 | NPC1 (0.48) | IDO1NPC1HTT | |
| SCHEMBL11290271 | 0.77 | PPARA (0.32) | PPARAPPARGPPARDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |
| EP-0002666-B1 | 1,2-BENZISOXAZOLYLOXY (OR THIO) ACETIC ACIDS AND RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-02-17 | — | — | EP | disclosed |