Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 9/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665524 | 1.00 | CDC25A (0.45) | CDC25AFFAR1LMNAKDM4EALDH1A1 | |
| SCHEMBL10667434 | 0.84 | LMNA (0.55) | CDC25ALMNAALDH1A1MAPTPTPN1 | |
| SCHEMBL10667429 | 0.84 | LMNA (0.55) | CDC25ALMNAALDH1A1MAPTPTPN1 | |
| SCHEMBL10665560 | 0.78 | S1PR1 (0.47) | CDC25ALMNAPTPN1HPGDSMN1; SMN2 | |
| SCHEMBL10665557 | 0.78 | S1PR1 (0.47) | CDC25ALMNAPTPN1HPGDSMN1; SMN2 | |
| SCHEMBL10666412 | 0.76 | POLB (0.41) | LMNAKDM4EALDH1A1MAPTPTPN1 | |
| SCHEMBL10666405 | 0.76 | POLB (0.41) | LMNAKDM4EALDH1A1MAPTPTPN1 | |
| SCHEMBL10661496 | 0.75 | CDC25A (0.44) | CDC25ALMNAKDM4EALDH1A1MAPT | |
| SCHEMBL10664577 | 0.75 | CDC25A (0.44) | CDC25ALMNAKDM4EALDH1A1MAPT | |
| SCHEMBL10666304 | 0.75 | CDC25A (0.44) | CDC25ALMNAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | claimed |
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |