Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666412 | 1.00 | POLB (0.41) | POLBKDM4ELMNAPTPN1ACP1 | |
| SCHEMBL10660826 | 0.76 | ALDH1A1 (0.54) | POLBKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL10665518 | 0.76 | CDC25A (0.45) | KDM4ELMNAPTPN1ACP1ALDH1A1 | |
| SCHEMBL9547641 | 0.65 | POLB (0.51) | POLBKDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL9547644 | 0.65 | POLB (0.51) | POLBKDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL10665584 | 0.64 | MEN1 (0.48) | POLBKDM4ELMNAPTPN1KMT2A | |
| SCHEMBL10665587 | 0.64 | MEN1 (0.48) | POLBKDM4ELMNAPTPN1KMT2A | |
| SCHEMBL10662753 | 0.62 | FAAH (0.51) | POLBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL8263368 | 0.62 | GALR3 (0.53) | POLBKDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL11116026 | 0.61 | MAPT (0.60) | POLBKDM4ELMNAPTPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |