Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | CDC25A | P30304 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665560 | 1.00 | S1PR1 (0.47) | S1PR1S1PR3CDC25APPARGNR1H4 | |
| SCHEMBL10666251 | 0.83 | S1PR1 (0.48) | S1PR1S1PR3CDC25APPARGLMNA | |
| SCHEMBL10666243 | 0.83 | S1PR1 (0.48) | S1PR1S1PR3CDC25APPARGLMNA | |
| SCHEMBL10667434 | 0.80 | LMNA (0.55) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10667429 | 0.80 | LMNA (0.55) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10665524 | 0.78 | CDC25A (0.45) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10665518 | 0.78 | CDC25A (0.45) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10664577 | 0.75 | CDC25A (0.44) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10666033 | 0.75 | CDC25A (0.44) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10661496 | 0.75 | CDC25A (0.44) | S1PR1S1PR3CDC25ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | claimed |