Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666251 | 1.00 | S1PR1 (0.48) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10667434 | 0.85 | LMNA (0.55) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10667429 | 0.85 | LMNA (0.55) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10665560 | 0.83 | S1PR1 (0.47) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10665557 | 0.83 | S1PR1 (0.47) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10669210 | 0.82 | PPARG (0.50) | LMNAHPGDSMN1; SMN2PPARGMAPT | |
| SCHEMBL10661496 | 0.76 | CDC25A (0.44) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10664577 | 0.76 | CDC25A (0.44) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10666304 | 0.76 | CDC25A (0.44) | S1PR1S1PR3CDC25ALMNAHPGD | |
| SCHEMBL10666033 | 0.76 | CDC25A (0.44) | S1PR1S1PR3CDC25ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |