Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665682 | 1.00 | FAAH (0.42) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10662771 | 0.81 | FAAH (0.54) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10666213 | 0.81 | FAAH (0.52) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10662770 | 0.81 | FAAH (0.54) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10667719 | 0.75 | FAAH (0.71) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10667710 | 0.75 | FAAH (0.71) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10668341 | 0.72 | FAAH (0.44) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10668343 | 0.72 | FAAH (0.44) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10668963 | 0.70 | AURKA (0.46) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL12297882 | 0.65 | FAAH (0.54) | FAAHMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | claimed |
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |