Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 5/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 5/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668970 | 1.00 | AURKA (0.46) | AURKAFAAHMGLLMEN1KMT2A | |
| SCHEMBL10668048 | 0.81 | FAAH (0.56) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10667434 | 0.74 | LMNA (0.55) | FAAHALDH1A1S1PR1S1PR3MAPT | |
| SCHEMBL10667429 | 0.74 | LMNA (0.55) | FAAHALDH1A1S1PR1S1PR3MAPT | |
| SCHEMBL10665686 | 0.70 | FAAH (0.42) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10666243 | 0.69 | S1PR1 (0.48) | FAAHALDH1A1S1PR1S1PR3MAPT | |
| SCHEMBL12297882 | 0.68 | FAAH (0.54) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10660629 | 0.68 | FAAH (0.48) | FAAHMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL17295254 | 0.67 | FAAH (0.64) | AURKAFAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL10668341 | 0.66 | FAAH (0.44) | FAAHMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | claimed |