Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624609 | 0.86 | ADAM17 (0.34) | DRD1DRD2HTR2BDRD3 | |
| SCHEMBL9624914 | 0.83 | SIGMAR1 (0.34) | DRD1DRD5CYP2D6MAPTHCN4 | |
| SCHEMBL9624838 | 0.81 | HCN4 (0.51) | MAPTHCN4DRD2HTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL9624535 | 0.80 | CYP3A4 (0.51) | MAPTHCN4DRD2HTR2BCYP3A4 | |
| SCHEMBL9623990 | 0.77 | SIGMAR1 (0.36) | DRD1DRD5MAPTHCN4DRD2 | |
| SCHEMBL10667423 | 0.76 | HCN4 (0.51) | DRD1DRD5MAPTHCN4DRD2 | |
| SCHEMBL9623765 | 0.75 | GNRHR (0.38) | DRD1DRD5CYP2D6MAPTHCN4 | |
| SCHEMBL9624622 | 0.75 | GNRHR (0.46) | DRD1DRD5CYP2D6MAPTHCN4 | |
| SCHEMBL10667609 | 0.74 | MAPT (0.42) | MAPTHCN4CYP3A4ALOX15BCHE | |
| SCHEMBL10668945 | 0.74 | HCN4 (0.34) | DRD1MAPTHCN4DRD2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737495-A | ANTIALLERGENS, ANTISCHEMIC, HYPOTENSIVE AGENTS | DR. KARL TOMAE, GMBH (DE) | 1988-04-12 | — | — | US | disclosed |
| EP-0204349-A2 | Heteroaromatic amine derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1986-12-10 | — | — | EP | disclosed |