Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665508 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBAPPKDM4EHSD17B10 | |
| SCHEMBL7940157 | 0.74 | KDM4E (0.50) | PRMT1ALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL11040911 | 0.72 | PRMT1 (0.67) | PRMT1BRD4ALDH1A1POLBAPP | |
| SCHEMBL2186275 | 0.70 | PRMT1 (0.63) | PRMT1BRD4ALDH1A1POLBRAB9A | |
| SCHEMBL2633374 | 0.67 | PRMT1 (0.59) | PRMT1BRD4ALDH1A1POLBRAB9A | |
| SCHEMBL9397268 | 0.67 | PRMT1 (0.55) | PRMT1ALDH1A1RAB9AKDM4EKMT2A | |
| SCHEMBL25019712 | 0.67 | MEN1 (0.52) | PRMT1ALDH1A1APPKDM4EHSD17B10 | |
| SCHEMBL438891 | 0.66 | PRMT1 (1.00) | PRMT1BRD4ALDH1A1POLBKDM4E | |
| SCHEMBL30487872 | 0.66 | PRMT1 (1.00) | PRMT1BRD4ALDH1A1POLBKDM4E | |
| SCHEMBL2005311 | 0.65 | PRMT1 (0.53) | PRMT1BRD4ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780501-A | Imidopolysiloxanes and method for making | GENERAL ELECTRIC COMPANY (US) | 1988-10-25 | — | — | US | disclosed |