SCHEMBL10666552

SCHEMBL10666552

CCCCCc1cccc(S([NH])(=O)=O)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.53
LIPG Q9Y5X9 3/20 0.53
CA2 P00918 2/20 0.47
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
XIAP P98170 1/20 0.43
TRPV1 Q8NER1 1/20 0.42
HTR6 P50406 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6444977 0.86 LPL (0.56) LPLLIPGCA2PPARGPPARA
SCHEMBL11828390 0.85 LPL (0.57) LPLLIPGCA2PPARGPPARA
SCHEMBL11426304 0.85 LPL (0.57) LPLLIPGCA2PPARGPPARA
SCHEMBL11266570 0.85 LPL (0.57) LPLLIPGCA2PPARGPPARA
SCHEMBL10666557 0.83 CA2 (0.65) LPLLIPGCA2TRPV1HTR6
SCHEMBL27554010 0.83 LPL (0.55) LPLLIPGCA2PPARGPPARA
SCHEMBL6580835 0.82 LPL (0.58) LPLLIPGCA2PPARGPPARA
SCHEMBL19333407 0.82 CA2 (0.63) LPLLIPGCA2PPARGPPARA
SCHEMBL6578230 0.82 LPL (0.58) LPLLIPGCA2PPARGPPARA
SCHEMBL11180128 0.82 LPL (0.58) LPLLIPGCA2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4792628-A ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-12-20 US disclosed