SCHEMBL6444977

SCHEMBL6444977

CCCCCc1cccc(S(=O)(=O)c2cccc(CCCCC)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.56
LIPG Q9Y5X9 3/20 0.56
HTR6 P50406 1/20 0.56
CA2 P00918 2/20 0.50
PPARG P37231 3/20 0.47
PPARA Q07869 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
TRPV1 Q8NER1 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11266570 0.98 LPL (0.57) LPLLIPGHTR6CA2PPARG
SCHEMBL11426304 0.98 LPL (0.57) LPLLIPGHTR6CA2PPARG
SCHEMBL11828390 0.98 LPL (0.57) LPLLIPGHTR6CA2PPARG
SCHEMBL27859841 0.95 HTR6 (0.57) LPLLIPGHTR6CA2PPARG
SCHEMBL10180036 0.90 HTR6 (0.66) LPLLIPGHTR6CA2SMN1; SMN2
SCHEMBL27876496 0.87 HTR6 (0.61) HTR6CA2SMN1; SMN2ALDH1A1TSHR
SCHEMBL27554010 0.86 LPL (0.55) LPLLIPGCA2PPARGPPARA
SCHEMBL10666557 0.86 CA2 (0.65) LPLLIPGHTR6CA2SMN1; SMN2
SCHEMBL10666552 0.86 LPL (0.53) LPLLIPGHTR6CA2PPARG
SCHEMBL6580835 0.85 LPL (0.58) LPLLIPGCA2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846619-B2 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. (JP) 2005-01-25 US disclosed
EP-1243437-B1 Leuco dye dispersion liquid and thermosensitive recording material using the same RICOH KK (JP) 2004-11-17 EP disclosed
US-20030060366-A1 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. 2003-03-27 US disclosed
EP-1243437-A1 Leuco dye dispersion liquid and thermosensitive recording material using the same Ricoh Company, Ltd. (JP) 2002-09-25 EP disclosed