Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD5 | P21918 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572030 | 0.88 | HTR1A (0.51) | DRD2HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL10570468 | 0.85 | DRD2 (0.52) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL10570868 | 0.84 | DRD2 (0.56) | DRD2HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL10570148 | 0.80 | DRD2 (0.59) | DRD2HTR1AHTR2AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL10569951 | 0.79 | DRD2 (0.58) | DRD2HTR1AHTR2AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL10569016 | 0.79 | DRD2 (0.58) | DRD2HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL10571081 | 0.77 | DRD2 (0.62) | DRD2HTR1AHTR2AHTR7ADRA1A | |
| SCHEMBL10570686 | 0.77 | DRD2 (0.66) | DRD2HTR1AHTR2AHTR7ADRA1A | |
| SCHEMBL11244354 | 0.76 | DRD3 (0.55) | DRD2HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL10569047 | 0.76 | DRD2 (0.50) | DRD2HTR1AHTR2AHTR7ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |