Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 13/20 | 0.55 |
| ▸ | DRD3 | P35462 | 13/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458346 | 0.87 | DRD2 (0.54) | ALOX5DRD2DRD3HDAC4HDAC1 | |
| Tagorizine SCHEMBL29359054 | 0.80 | ALOX5 (1.00) | ALOX5DRD2DRD3 | |
| Tagorizine SCHEMBL6008778 | 0.80 | ALOX5 (1.00) | ALOX5DRD2DRD3 | |
| Tagorizine SCHEMBL6008781 | 0.80 | ALOX5 (1.00) | ALOX5DRD2DRD3 | |
| Tagorizine SCHEMBL139324 | 0.80 | ALOX5 (1.00) | ALOX5DRD2DRD3 | |
| SCHEMBL5557294 | 0.79 | NAMPT (0.51) | ALOX5DRD2DRD3HDAC4HDAC1 | |
| SCHEMBL5557428 | 0.77 | DRD2 (0.48) | ALOX5DRD2DRD3LMNA | |
| SCHEMBL9834884 | 0.77 | ALOX5 (0.94) | ALOX5DRD2DRD3 | |
| SCHEMBL9834879 | 0.77 | ALOX5 (0.94) | ALOX5DRD2DRD3 | |
| SCHEMBL22321657 | 0.75 | DRD2 (0.65) | ALOX5DRD2DRD3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778796-A | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |