Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10664612 | 0.86 | ADRB3 (0.47) | ADRB3ADRB2 | |
| SCHEMBL10668669 | 0.83 | ADRB2 (0.52) | ADRB3ADRB2 | |
| SCHEMBL11747553 | 0.82 | ADRB3 (0.74) | ADRB3ADRB2 | |
| SCHEMBL3136753 | 0.81 | ADRB3 (0.72) | ADRB3ADRB2 | |
| Hydrochloric Acid SCHEMBL11744017 | 0.81 | ADRB3 (0.72) | ADRB3ADRB2 | |
| Hydrochloric Acid SCHEMBL11669931 | 0.80 | ADRB3 (0.71) | ADRB3ADRB2 | |
| SCHEMBL7610796 | 0.79 | ADRB3 (0.67) | ADRB3ADRB2 | |
| SCHEMBL10669667 | 0.79 | HIF1A (0.62) | ADRB3ADRB2 | |
| SCHEMBL10667097 | 0.77 | HIF1A (0.49) | ADRB3ADRB2 | |
| SCHEMBL10665538 | 0.77 | HIF1A (0.42) | ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721717-A | α-(aminoalkylaminomethyl)phenylmethanols, composition containing them, and use thereof to treat certain heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-01-26 | — | — | US | disclosed |