Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.64 |
| ▸ | F3 | P13726 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | XDH | P47989 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11393308 | 0.92 | F3 (0.64) | TRPM8F3THRBATMGSK3B | |
| SCHEMBL11393305 | 0.92 | F3 (0.64) | TRPM8F3THRBATMGSK3B | |
| SCHEMBL11388643 | 0.82 | HDAC8 (0.57) | TRPM8F3THRBATMGSK3B | |
| SCHEMBL11388645 | 0.82 | HDAC8 (0.57) | TRPM8F3THRBATMGSK3B | |
| SCHEMBL600597 | 0.81 | HTT (0.70) | TRPM8F3THRBATMGSK3B | |
| SCHEMBL154420 | 0.81 | HTT (0.70) | TRPM8F3THRBATMGSK3B | |
| SCHEMBL8877437 | 0.80 | KMT2A (0.55) | TRPM8ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL8877446 | 0.80 | KMT2A (0.55) | TRPM8ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL11147619 | 0.79 | HSD17B3 (0.58) | TRPM8HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL18364671 | 0.79 | HTT (0.61) | TRPM8F3THRBATMGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |